IMPAIRED AUTOPHAGY CONTRIBUTES TO THE AGGRAVATED DETERIORATION OF OSTEOARTHRITIS ARTICULAR CARTILAGE BY PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR α DEFICIENCY, ASSOCIATED WITH DECREASED ERK AND AKT ACTIVATION

Abstract Background Although the chondroprotection of peroxisome proliferator-activated receptor α (PPARα) activation against osteoarthritis (OA) has been revealed, the regulatory mechanism of PPARα deficiency to aggravate osteoarthritic cartilage BEARD OIL deterioration remains unclear.Here, we aimed to investigate whether and how autophagy is

Advances in the adoption of technological innovations represent a great driver to improve the competitiveness of the Italian extra virgin olive oil (EVOO) industry.This work assesses the efficiency of an innovative extraction plant (with low oxidative impact, heating of paste before malaxation and a special decanter that avoids the final vertical c

The purpose of this study was to systematically review the Brazilian literature on the prevalence of obesity and associated BEARD OIL factors in adolescents.The literature search was carried out in the electronic databases Pubmed and Bireme, using the keywords: obesity, overweight, BMI, adolescents and Brazil.The following inclusion criteria were c

Technological advances have dramatically improved precision agriculture, and accurate crop classification is a key aspect of precision agriculture (PA).The flexibility and real-time nature of UAVs have led them to become an important tool for acquiring agricultural data and enabling precise crop classification.Currently, crop identification relies

Introduction: DNA barcode, a molecular marker, is used to distinguish among the closely related species, and it can be Phone Accessories applied across a broad range of taxa to understand ecology and evolution.MaturaseK gene ( matK ) and rubisco bisphosphate carboxylase/oxygenase form I gene ( rbcL ) of the chloroplast are highly conserved in a pla